Sandra's no-show follows a report in InTouch magazine that claims her husband of four years Jesse James had an affair with a heavily tattooed, very skanky looking model.
"I asked him, 'What’s going on with you and Sandra?'," she told InTouch. "Jesse was evasive.
"He said, 'She doesn’t live here. She has a house in Austin. She is filming, and I can’t talk about it.'"
A statement from Warner Brothers says that Sandra missed last night's UK event "due to unforeseen personal reasons".
Sandra and Jesse have no children together but they were recently granted full custody of Jesse's five-year-old daughter from his previous marriage to heavily tattooed druggie porn star Janine Lindemulder.
...Guess he's got a thing for tattoos, eh?
If the affair claims turn out to be true, Sandra could be the latest victim of the 'Best Actress Oscar curse'. Six out of the last ten winners (Kate Winslet, Reese Witherspoon, Hilary Swank, Chalize Theron, Julia Roberts and Halle Berry) have broken up with their partners soon after winning the award.
If Sandra ends up single, she'll be the unlucky seventh!